Effects of technogenic pollutants on chicken embryos / Number 1 / Volume 31 (2018) / Current Issues in Pharmacy and Medical Sciences / Current Issues of Pharmacy and Medical Sciences

Effects of technogenic pollutants on chicken embryos

Curr Issues Pharm Med Sci., Vol. 31, No. 1, 34-36

Sabrie Zinabadinova, Viktoria Lavrinenko, Rostislav Kaminsky,
Alina Korsak, Liudmyla Sokurenko, Yuri Chaikovsky

O.O. Bogomolets National Medical University, Department of Histology and Embryology, T. Shevchenko boulevard 13, 01601 Kyiv, Ukraine

10.1515/cipms-2018-0008

Abstract

Increasing interest in nanomaterials can be explained by their broad involvement in many fields of industry and medicine. It is known that carbon black and crysotile asbestos behave like nanosized objects. They are wide spread in environment and have close contact with living organisms. The aim of our study was to define the effects of carbon black and crysotile asbestos on structures of the developing organism.

We used chicken embryos as a model for our study. Total amount of 77 eggs was divided in three groups: one control and two experimental with introduced carbon black and asbestos respectively. Researched materials were injected in the yolk on the third day of incubation and tissues for study were taken during early, middle and late stages of incubation. Histological and electron microscopy methods were used.

Carbon black and asbestos introduction caused underdevelopment of embryos and vessels depletion in blood islands of the yolk sac. Asbestos slowed down angiogenesis. Soot particles caused integrity violation of vessels and led to extravasation. The manifestations of soot influence were damages to blood circulatory system and structural disorders on cellular level. Introduction of chrysotile asbestos mostly resulted in compensatory-adaptive reactions like increasing in hematopoiesis and transcytosis in endotheliocytes.

Full Text

Keywords

asbestos, carbon black, chicken embryo, yolk sac.

References

Baur X., Wilken D. Effect of asbestos fiber dust exposures on lung function--a systematic review. Pneumologie. 2010; 64 (2): 81-110. Google Scholar
Saputra D., Yoon J.H., Park H., Heo Y., Yang H., Lee E.J. et al. Inhalation of carbon black nanoparticles aggravates pulmonary inflammation in mice. Toxicol Res. 2014; 30 (2): 83-90. Google Scholar
Barua S., Mitragotri S. Challenges associated with Penetration of Nanoparticles across Cell and Tissue Barriers: A Review of Current Status and Future Prospects. Nano Today. 2014; 9(2): 223-243. Google Scholar
Funahashi S., Okazaki Y., Ito D., Asakawa A., Nagai H., Tajima M. et al. Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells. J Clin Biochem Nutr. 2015; 56 (2): 111-17. Google Scholar
Kaminsky F. Rostislav, Sokurenko M. Liudmyla, Chaikovsky B. Yuri Status of rats myocardium under subchronic mercury exposure and its pharmacological correction Curr Issues Pharm Med Sci., 2016; 29(4): 167-70. Google Scholar
Omelchuk S., Aleksijchuk V., Sokurenko L., Blagaia A., Prudchenko S. Characteristics of rat liver exposed to nanoparticles of lead compounds. Georgian Med News. 2016 Des;(261):94-9. Google Scholar
Oberdorster G., Oberdorster E., Oberdorster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect. 2005; 113 (7): 823-39. Google Scholar
Al Moustafa A., Mfoumou E., Roman D.E., Nerguizian V., Alazzam A., Stiharu I. et al. Impact of single-walled carbon nanotubes on the embryo: a brief review. Int J Nanomedicine. 2016; 11: 349-355. Google Scholar
Celá P, Veselá B., Matalová E., Večeřa Z., Buchtová M. Embryonic toxicity of nanoparticles. Cells Tissues Organs. 2014; 199 (1): 1-23. Google Scholar
Fernandes R., Costola-Souza C., Sarmento C., Gonçalves L., Favaron Ph. O., Miglino M. A. Placental tissues as sources of stem cells. Open Journal of Animal Sciences. 2012; 2: 166-173. Google Scholar
Guedes P., Oliveira B., Manso P., Caputo L., Cotta-Pereira G., Pelajo-Machado M. Histological analyses demonstrate the temporary contribution of yolk sac, liver, and bone marrow to hematopoiesis during chicken development. PLoS One. 2014; 9(3). Google Scholar
Lavrinenko V.E., Zinabadinova S.S., Shobat L.B., Sokurenko L.M., Chaikovsky Yu.B. Influence of nanodiamonds and carbon nanowires on survival and cells structure in chicken embryo. Georgian Medical News. 2016; 6 (255): 93-9. Google Scholar
Zinabadinova S.S. Features of structural and functional conditions of chiken embryo liver which are caused by asbestos fibers and carbon nanowires. Bulletin of problems in biology and medicine. 2015; 2/1 (118): 265-9. Google Scholar
Lavrinenko V. E. Biological effect of nanodiamonds and soot on structural and functional conditions of chiken embryo liver and kidneys. Bulletin of problems in biology and medicine. 2015; 2/1 (118): 269-73. Google Scholar

Calendar

December 2024

All events

Mon	Tue	Wed	Thu	Fri	Sat	Sun
						01
02	03	04	05	06	07	08
09	10	11	12	13	14	15
16	17	18	19	20	21	22
23	24	25	26	27	28	29
30	31

Mon	Tue	Wed	Thu	Fri	Sat	Sun
						01
02	03	04	05	06	07	08
09	10	11	12	13	14	15
16	17	18	19	20	21	22
23	24	25	26	27	28	29
30	31